Homogenization - Cosmetic, Pharma & Biotech |
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Cosmetic Homogenizer ApplicationsHigh-pressure homogenization is essential to the quality and stabilization of beauty creams, lotions, nail varnishes, shampoos, toothpastes, and emulsions containing different oils since it is a very effective way to create the exact required product texture (via particle size reduction) while at the same time creates very stable product compared to the traditional devices such as agitators, stirrers, rotor-stator devices or colloid mills. This is achieved by reducing the particle size and uniformity under conditions of extreme pressure, shear and stress. The result is a homogeneous effective product with superior stability and shelf life. It is well known fact that one of the limiting factors in the performance of some cosmetic product, for instance beauty creams, is its ability to be absorbed into the skin. Drastic particle size reduction enables the skin to absorb the active ingredients in these creams as the surface area increases after the homogenization (vs volume ratio). High-pressure homogenization (also known as micronization) also ensures the most efficient use of the active agents, thus reducing product costs. A typical Very High Pressure (VHP) homogenizer for cosmetic applications includes the following:
Biotechnology Homogenizer ApplicationsHigh-pressure homogenization is widely used for cell rupture (cell rupturing, cell disruption) applications in order to extract intra-cell substances without using solvents or other chemicals for the cell wall breakage. The main purpose is to release intercellular substances such as proteins, enzymes, and vitamins that are found in high concentrations in various organisms such as yeasts, algae and bacteria (and other biological products). High-pressure homogenizers are very effective and efficient for cell rupture operations and can often maximize the yield from valuable source material while keeping product quality at a very high level. A typical homogenizer skid for cell rupture applications includes the following:
The skid systems are built to the requirements of the ASME BPE standards, and Niro Soavi manufactures the homogenizer units in compliance with the ISO 9001 QA program. Pharmaceutical Homogenizer ApplicationsHomogenization (known in the pharmaceutical industry as micronization) is the process of reducing the particle sizes of pharmaceutical products, under very high pressures, sheer, turbulence, acceleration and impact, to make them more stable and clinically effective. The bioavailability of the product increases and the tolerance of some otherwise borderline drugs can improve. The emulsion, suspension or solution is pumped into the high-pressure homogenizer after which it is forced through a special homogenization valve at extremely high pressures (up to 1,500 bar / 21,750 PSI). The particles enter the homogenizer with 500 µm maximum sizes, after the treatment the large particles are dispersed and reduced, the particle size typically range from 0.4 to 1 micron depending on the specific application. High-pressure homogenization in the pharmaceutical industry has proven its ability to make more stable product, with better active ingredient dispersion, than has been achieved with conventional stirrers, rotor-stator devices or colloid mills. It achieves this by reducing the particle size and uniformity under conditions of extreme pressure and stress. The result is a more clinically effective product with greater stability and shelf life. A typical Niro Soavi homogenizer for pharmaceutical applications features the following:
Typical Cosmetic, Biotech and Pharma Applications:
Niro Soavi homogenizers are engineered to be completely reliable to minimize service and down time. In addition, our network of experienced after-sales service engineers and technicians are always available to provide planned or emergency maintenance whenever and wherever it is needed. Leading Technologies. Individual Solutions. |
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